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DNAL1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 158091AP

Catalog No. 50-173-0497


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Description

Description

DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.
Specifications

Specifications

DNAL1
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q05A62, Q4LDG9
C14orf168, DNAL1, Dynein light chain 1, axonemal
Rabbit
IgG
150 μL
-20°C
Primary
105000, 685664, 83544
Immunoprecipitation, Western Blot
Unconjugated
DNAL1
Liquid
Dnal1
DNAL1 Fusion Protein Ag8545
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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