DOCK10 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 168341AP
DescriptionThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|dedicator of cytokinesis 10, DOCK10, DRIP2, KIAA0694, Nbla10300, ZIZ3, Zizimin 3|
|210293, 301556, 55619|
|DOCK10 Fusion Protein Ag10486|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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