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Medchemexpress LLC Docosanoic acid | 112-85-6 | 99.4% | 340.59 | 10 G

Supplier: Medchemexpress LLC HYW01304910G
Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid that inhibits the double-stranded DNA (dsDNA) binding activity of the p53 DNA binding domain with a Kd of 12 nM. It has low bioavailability and can increase cholesterol in humans.
- Inhibits dsDNA binding activity of wild-type p53 DBD with 50% inhibition at 0.41 nmol.
- Affects cholesterol levels in humans.
- Impacts fat deposition in rats, reducing visceral fat and increasing fatty acid excretion.
- Low bioavailability leads to reduced absorption and body weight in rats.
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