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Thermo Scientific™ Lab Vision™ DOG1, Rabbit Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Dog1, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio.

$310.00 - $2270.00

Specifications

Antigen DOG1
Clone SP31
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 5
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
RM9132R7
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Thermo Scientific™
RM9132R7
Ready-to-use for IHC (UVLP) 7mL
Each for $785.50
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RM9132RQ
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Thermo Scientific™
RM9132RQ
Ready-to-use for IHC (Quanto) 12mL
Each for $811.50
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RM9132S
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Thermo Scientific™
RM9132S
Culture Supernatant with Azide 1mL
Each for $2,270.00
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RM9132S0
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Thermo Scientific™
RM9132S0
Culture Supernatant with Azide 100μL
Each for $310.00
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RM9132R1
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Thermo Scientific™
RM9132R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

Ensure accurate, reproducible results in immunohistochemistry experiments with Thermo Scientific™ Dog1, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

DOG1 is a cell surface protein of unknown function selectively expressed in GIST. Among GIST cases with KIT mutations the DOG1 antibody identified 11% more cases than c-Kit antibody. DOG1 identifies vast majority of both c-Kit negative and PDGFRA mutated GIST cases that may still benefit from imatinib mesylate (Gleevac), an inhibitor of the kit tyrosin kinase. In addition, DOG1 immunoreactivity is seen in fewer cases of mesanchymal, epithelial tumors and melanomas when compared with c-Kit. The use of this highly sensitive and specific novel marker will increase the accuracy of GIST diagnosis.

Host Species: Rabbit

Clone: SP31

Isotype: IgG

Species Reactivity: Human. Others not known.

Immunogen: Synthetic peptide of human DOG1

Molecular Weight: 78 kDa

Positive Control: Gastrointestinal Stromal Tumors

Cellular Localization: Cytoplasmic and Membranous

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Specifications

DOG1
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Primary
SP31
Monoclonal
Rabbit
Cancer and Tumor Biology
Synthetic peptide of human Dog1
SDS
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