DOK7 Monoclonal Antibody (OTI1A9), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA504801

Catalog No. 50-167-5412

Description

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: DOK7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q18PE0, Q18PE1
• Gene Symbols: Dok7
• Immunogen: Full length human recombit protein of human DOK7 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1A9
• Conjugate: Unconjugated
• Gene: DOK7
• Gene Alias: C4orf25, CMS10, CMS1B
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 231134, 285489
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid