Tocris™ Donitriptan hydrochloride

5-HT1B/1D agonist

Manufacturer: Tocris™ 3665/10

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Catalog No. 36-651-0R

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For Research Use Only


    Inhibitors Donitriptan hydrochloride
    Purity >98
    Molecular Weight 439.94
    Quantity 10mg
    Product Type Donitriptan hydrochloride

    Brain penetrant 5-HT1B/1D agonist (pKi values are 9.3 and 9.4 for 5-HT1D and 5-HT1B respectively). Inhibits capsaicin-induced external carotid vasodilation and produces selective carotid vasoconstriction in various animal species. Displays antimigraine activity.

    • Chemical Name: 1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazine hydrochloride
    • Formula: C23H25N5O2.HCl
    • CAS Number: 170911-68-9
    • Solubility: Soluble to 50mM in DMSO
    • Purity: >98

  • Description & Specifications

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