Dopamine Transporter Mouse anti-Mouse, Rat, Clone: mAb16, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524796
DescriptionDopamine transporter (DAT), also known as solute carrier family 6, is principally expressed in the presynaptic membrane of dopaminergic nerve terminals where it mediates the rapid removal of dopamine from the synaptic cleft after neuronal stimulation. As such, DAT plays an important role in regulating the availabity of dopamine in the synaptic cleft and thus in modulating the physiological functions of dopamine. The re-uptake of dopamine by the DAT is inhibited by psychostimulants such as cocaine and amphetamine.
|tris glycine with 0.15M NaCl and 0.05% sodium azide; pH 7.5|
|DA transporter, DATDAT1Solute carrier family 6 member 3, sodium-dependent dopamine transporter, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Synthetic peptide corresponding to the N-terminus of rat DAT1.|
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