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DTYMK Monoclonal Antibody (OTI1E12), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Supplier: OriGene TA503490
Description
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.Specifications
| DTYMK | |
| Monoclonal | |
| 0.42 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P23919 | |
| DTYMK | |
| Full length human recombit protein of human DTYMK produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Western Blot | |
| OTI1E12 | |
| Unconjugated | |
| DTYMK | |
| CDC8, PP3731, TMPK, TYMK | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 1841 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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