Invitrogen™ DVL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527965

Catalog No. PIPA527965

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (80%), Xenopus laevis (83%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Disheveled DVL2 is a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

Specifications

• Antigen: DVL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DVL2
• Gene Alias: dishevelled 2; dishevelled 2 (homologous to Drosophila dsh); dishevelled 2, dsh homolog; dishevelled 2, dsh homolog (Drosophila); dishevelled segment polarity protein 2; dishevelled, dsh homolog 2; dishevelled-2; DSH homolog 2; Dvl2; Dvl-2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2; sb:eu471; Segment polarity protein dishevelled homolog DVL-2; wu:fc05d12; wu:fo71e09; wu:fp54a02; zgc:55372
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13543, 1856
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.04 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14641, Q60838
• Gene Symbols: DVL2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 223 and 550 of Human Dishevelled 2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG