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Invitrogen™ Dynabeads™ SARS-CoV-2 Spike

The Dynabeads™ SARS-CoV-2 Spike consists of superparamagnetic beads coupled with a trimeric spike protein. The spike protein is a patented recombinant trimeric structure combining the S1 subunit, including the receptor binding domain (RBD), and the S2 subunit found on the surface of the SARS-CoV-2 virus.

$350.00 - $1446.00

Specifications

Certifications/Compliance ISO 13485
Concentration 1 mg/mL
Content And Storage The beads are supplied in 0.05 M Tris-buffered saline (TBS) with 0.001% Tween-20 and 0.02% NaN3.

Store at 2–8°C.

Detection Method Absorbance at 450 nm
Color Brown beads in colorless suspension
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Products 2
Catalog Number Mfr. No. Volume (Metric) Price Quantity & Availability  
Catalog Number Mfr. No. Volume (Metric) Price Quantity & Availability  
18100D
Encompass
View Documents
Invitrogen™
18100D
3 mL
Each for $350.00
Add to cart
 
18100DFIVE
Encompass
View Documents
Invitrogen™
18100DFIVE
5 x 3 mL
Each for $1,446.00
Add to cart
 
Description

Description

  • Dynabeads SARS-CoV-2 Spike consists of superparamagnetic beads coupled with a trimeric spike protein
  • The spike protein is a patented recombinant trimeric structure combining the S1 subunit, including the receptor binding domain (RBD), and the S2 subunit found on the surface of the SARS-CoV-2 virus
  • Virus spike protein binds to human host cells via the angiotensin-converting enzyme 2 (ACE2) receptor to initiate virus attachment, as well as to antibodies produced in the body as a response to SARS-CoV-2 infection
  • This Dynabeads SARS-CoV-2 Spike is also included in enzyme‐linked immunosorbent assay (ELISA) kits designed to detect and quantify the level of human SARS-CoV-2 IgG, IgM, and Total Ig antibodies from serum and plasma samples
  • Kits can be used manually with a DynaMag-96 magnet or in an automated fashion using a KingFisher instrument
  • Magnetic beads significantly improve the binding kinetics to cut the ELISA incubation time in half (45 minutes) compared to the more conventional plate-based ELISAs (90 minutes)
  • Since the spike protein binds host cells to initiate the entrance of SARS-CoV-2 virus into the epithelial cells of the lungs via ACE2, the beads may also be used for isolation of ACE2+ cells or for ACE2 protein purification
  • Dynabeads-facilitated automation limits hands-on time
  • Also available in SARS-CoV-2 ELISA kits
  • For research use only, not for use in diagnostic procedures
Specifications

Specifications

ISO 13485
The beads are supplied in 0.05 M Tris-buffered saline (TBS) with 0.001% Tween-20 and 0.02% NaN3.

Store at 2–8°C.

Brown beads in colorless suspension
Monosized, superparamagnetic polystyrene magnetic beads
KingFisher™ Flex or Apex Instruments, DynaMag™-96 Side Skirted, Magnetic 96-Well Separator, ELISA Plate Reader (450 nm)
Dynabeads™ magnetic beads
2.7 μm
1 mg/mL
Absorbance at 450 nm
Binding of human antibodies towards SARS-CoV-2 (Spike trimer)
Dynabeads™ magnetic beads coated with trimeric SARS-CoV-2 spike protein
Yes, on KingFisher™ Flex or Apex instruments
Wet ice (2° to 8°C)
SDS
Product Certifications

For research use only. Not for use in diagnostic procedures.

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