Invitrogen™ Dynamin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519800

Catalog No. PIPA519800

Description

Heat mediated antigen retrieval recommended prior to tissue staining. This antibody is predicted to react with cow, Xenopus laevis and zebrafish based on sequence homology.

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

Specifications

• Antigen: Dynamin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DNM2
• Gene Alias: b2b2159Clo; CMT2M; CMTDI1; CMTDIB; DI-CMTB; Dnm2; DYIIAAB; Dyn2; dynamin 2; dynamin II; Dynamin UDNM; Dynamin-2; DYNII; LCCS5; Udnm
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13430, 1785, 25751
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P39052, P39054, P50570
• Gene Symbols: DNM2
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 850 - 870 of Human Dynamin 2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG