DYNC1LI1 Mouse anti-Human, Clone: OTI2B6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525217
DescriptionActs as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|DNCLI1, LIC1, DLC-A, cytoplasmic dynein 1 light intermediate chain 1, dynein light chain A, dynein light chain-A, dynein light intermediate chain 1, cytosolic, dynein, cytoplasmic, light intermediate polypeptide 1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|Full length human recombit protein of DYNC1LI1 produced in HEK293T cell|
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