Tocris E 64
Potent and irreversible cysteine protease inhibitor
Manufacturer: Tocris 5208/10
DescriptionPotent and irreversible cysteine protease inhibitor (IC50 values are 1.4, 2.5 and 4.1nM for cathepsin K, L and S respectively. Also inhibits papain, calpain, cathepsin B and cathepsin H. Has no effect on serine proteases. Reduces HSC-3 tongue cancer cell invasion and induces oxidative stress and apoptosis in filarial parasites. Also inhibits autophagy-associated lysosomal degradation in vitro.
- Chemical Name: (2S,3S)-3-[[[(1S)-1-[[[4-(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic acid
- Formula: C15H27N5O5
- CAS Number: 66701-25-5
- Solubility: Soluble to 20mM in water
- Purity: >98
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok