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E2F3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA595394
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Synthetic peptide sequence: 278-320aa, QSCTLDLKLLTEDSENQRLAYVTYQDIRKISGLKDQTVIVVKA. Reconstitution information: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner.
|0.2mg sodium phosphate with 0.9MG NaCl, 0.9MG NaCl and 0.05MG sodium azide, 0.05MG sodium azide|
|A synthetic peptide corresponding to a sequence at the C-terminus of human E2F3, identical to the related mouse sequence.|
|Human, Mouse, Rat|
|Transcription factor E2F3; E2F-3; E2F3; KIAA0075|
|13557, 1871, 291105|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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