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EAPP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 169311AP

Catalog No. 50-173-1269


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Description

Description

This protein may play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The C-terminal of EAPP binds the N-terminal of E2F1 and also interacts with E2F2 and E2F3, but not E2F4.
Specifications

Specifications

EAPP
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q56P03, Q5BU09
BM036, C14orf11, E2F associated phosphoprotein, EAPP
Rabbit
IgG
150 μL
-20°C
Primary
299043, 55837, 66266
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
EAPP
Liquid
EAPP
EAPP Fusion Protein Ag10403
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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