EBV Early Antigens Mouse anti-Virus, Alexa Fluor 350, Clone: 1108-1, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234516AF350
DescriptionEBV Early Antigens Monoclonal antibody specifically detects EBV Early Antigens in Virus samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen).
|EBV Early Antigens|
|Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen|
|Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera|
|Protein A purified|
|Store at 4°C in the dark.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot|
|Alexa Fluor™ 350|
|50 mM sodium borate with 0.05% sodium azide|
|Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.|
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