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EBV Early Antigens Mouse anti-Virus, Alexa Fluor™ 532, Clone: 1108-1, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234516AF532

Catalog No. NP23416A32


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Description

Description

EBV Early Antigens Monoclonal antibody specifically detects EBV Early Antigens in Virus samples. It is validated for Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen).
Specifications

Specifications

EBV Early Antigens
1108-1
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Conjugated, Purified
Affinity purified early antigen polypeptides from induced Raji cells precipitated with African Burkitt′s lymphoma sera
Protein A purified
Store at 4°C in the dark.
Monoclonal
Virus
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
Alexa Fluor™ 532
50 mM sodium borate with 0.05% sodium azide
Mouse
IgG1 Kappa
0.1 mL
Primary
Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness. The EBV-induced early antigens (Ea) are among several antigen complexes that have been identified in EBV-infected cells. The Ea complex is composed of diffuse (Ea-D) and restricted (Ea-R) components. The activity of Ea-D is suppressed during latent infection. BMRF1, the gene that encodes for Ea-D, is closely associated with the gene encoding for EBV DNA polymerase, and Ea-D is essential for the activity of this polymerase. Ea-D forms a complex with EBV DNase and, together, they may play a role in viral replication.
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