Invitrogen™ ECE2 Monoclonal Antibody (233914)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA523941

Catalog No. PIMA523941

Description

In Western blots, 30% cross-reactivity with recombinant human (rh) ECE-1 and no cross-reactivity with rhKELL is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Specifications

• Antigen: ECE2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P0DPD6
• Gene Symbols: Ece2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ECE-2 Val104-Leu787.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 233914
• Conjugate: Unconjugated
• Gene: Ece2
• Gene Alias: 1810009K13Rik; 6330509A19Rik; 9630025D12Rik; BB127715; Ece2; ECE-2; ECE-2a-1; ECE-2a-2; ECE-2b-1; ECE-2b-2; EEF1A lysine methyltransferase 4; EEF1AKMT4; EEF1AKMT4-ECE2; EEF1AKMT4-ECE2 readthrough transcript protein; endothelin converting enzyme 2; endothelin converting enzyme-2; endothelin-converting enzyme 2; Endothelin-converting enzyme 2 region; endothelin-converting enzyme 2a-1; endothelin-converting enzyme 2a-2; endothelin-converting enzyme 2b-1; endothelin-converting enzyme 2b-2; KIAA0604; Methyltransferase-like region; UNQ403/PRO740
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 9718
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized