Tocris™ Efonidipine hydrochloride monoethanolate

Ca2+ channel blocker (L- and T-type)

Manufacturer: Tocris™ 3733/10

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Catalog No. 37-331-0R

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For Research Use Only


    Product Type Efonidipine hydrochloride monoethanolate
    Inhibitors Efonidipine hydrochloride monoethanolate
    Purity >99
    Molecular Weight 714.18
    Quantity 10mg

    Selective blocker of L-type and T-type Ca2+ channels. Displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers display different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity.

    • Chemical Name: 5-(5,5-Dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester hydrochloride monoethanolate
    • Formula: C34H38N3O7P.HCl.C2H5OH
    • CAS Number: 111011-76-8
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >99

  • Description & Specifications

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