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Tocris™ Efonidipine hydrochloride monoethanolate

Ca2+ channel blocker (L- and T-type)

Manufacturer:  Tocris™ 3733/10

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Catalog No. 37-331-0R

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For Research Use Only



Selective blocker of L-type and T-type Ca2+ channels. Displays minimal inhibition of N- and P/Q-type channels and no inhibition of R-type channels. R(-) and S(+)-enantiomers display different channel selectivity; S(+)-Efonidipine blocks L-type and T-type channels whereas R(-)-Efonidipine displays selectivity for T-type channels. Exhibits antihypertensive activity.
  • Chemical Name: 5-(5,5-Dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid 2-[phenyl(phenylmethyl)amino]ethyl ester hydrochloride monoethanolate
  • Formula: C34H38N3O7P.HCl.C2H5OH
  • CAS Number: 111011-76-8
  • Solubility: Soluble to 100mM in DMSO
  • Purity: >99
Description & Specifications


Efonidipine hydrochloride monoethanolate
Efonidipine hydrochloride monoethanolate
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