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EGFR Antibody (DH8.3), Janelia Fluor™ 646 - Mutant, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP250599JF646
Description
EGFR Monoclonal specifically detects EGFR in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry.Specifications
EGFR | |
Monoclonal | |
Janelia Fluor 646 | |
50mM Sodium Borate with 0.05% Sodium Azide | |
EGFR | |
Synthetic peptide corresponding to the junctional region of the truncated receptor LEEKKGNYVVTDHC,conjugated to keyhole limpet haemcyanin. | |
0.1 mL | |
Primary | |
Clone DH8.3 of EGF R/ErbB1 antibody is specific for Truncated EGFR which is also called EGFR type III, EGFRvIII or delta-EGFR (characterized by a deletion of 267 amino acids in the extracellular domain, leading to a receptor which is unable to bind ligand yet is constitutively active). Because of its impaired internalisation and degradation, EGFRvIII is known to enhance tumourigenesis. NOTE: Clone DH8.3 DOES NOT cross-react with full length or wildtype EGFR (wtEGFR). | |
Store at 4°C in the dark. | |
IgG1 |
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry | |
DH8.3 | |
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry | |
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1 | |
Mouse | |
Protein G purified | |
Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases | |
1956 | |
Human | |
Purified |
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