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EGFR, Mouse anti-Human, DyLight 650, Clone: 31G7 + GFR1195, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP247743C
DescriptionEGFR Monoclonal antibody specifically detects EGFR in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence.
|31G7 + GFR1195|
|Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence|
|Human EGFR purified from A431 cells (31G7); Recombinant human EGFR protein (GFR1195)|
|Protein A or G purified|
|Store at 4°C in the dark.|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)|
|50mM Sodium Borate with 0.05% Sodium Azide|
|avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 184.108.40.206, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1|
|Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases|
|This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.|