eIF3d Mouse anti-Human, Clone: OTI14D6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526950
DescriptioneIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RP5-1119A7.12-003, EIF3S7, eIF3-p66, eIF3-zeta, eIF-3-zeta, eIF3 p66, eukaryotic translation initiation factor 3 subunit 7, eukaryotic translation initiation factor 3 subunit D, eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa, translation initiation factor eIF3 p66 subunit|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of EIF3D produced in HEK293T cell|
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