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eIF3i Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551250

Catalog No. PA551250


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Description

Description

The antibody detects endogenous levels of total EIF3I protein.

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Specifications

Specifications

EIF3I
Polyclonal
Unconjugated
EIF3I
Liquid
EIF3I
Fusion protein of human EIF3I
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q13347
TRIP1, EIF3S2, TRIP-1, PRO2242, eIF3-p36, eIF3-beta
Rabbit
IgG
100 μL
-20°C
Primary
8668
Documents
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