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EIF4B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 179171AP

Catalog No. 50-173-1873


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Description

Description

eIF4B is a multidomain eukaryotic translation initiation factor with a range of activities. It contains one RRM (RNA recognition) domain, a consensus RNA-binding site (RNP-CS) near the N terminus, and a central domain rich in aspartic acid, arginine, tyrosine, and glycine (DRYG). The DRYG domain of eIF4B helps in self-association and interaction with the p170 subunit of eIF3. eIF4B binds to both mRNA and 18S ribosomal RNA and thus acts as a bridge between the mRNA and the 40S ribosomal subunit during translation initiation. The ATPase and RNA helicase activity of the DEAD box protein eIF4A is stimulated by eIF4B and thus functions in close association with eIF4F a heterotrimeric protein that binds to mRNA cap structure and unwinds inhibitory secondary structure in the 5 ft. untranslated region of eucaryotic mRNAs in an ATP-dependent manner. Ubiquitous expression is seen in most of the tissues.
Specifications

Specifications

EIF4B
0.45 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P23588, Q8BGD9
EIF 4B, EIF4B, PRO1843
Rabbit
IgG
150 μL
-20°C
Primary
1975, 300253, 75705
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
EIF4B
Liquid
Eif4b
EIF4B Fusion Protein Ag12325
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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