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EIF4E Mouse anti-Human, Clone: OTI5D11, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503042

Catalog No. 50-167-4015


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Description

Description

All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.
Specifications

Specifications

EIF4E
Monoclonal
0.5 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P06730
AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1977
Immunohistochemistry (Paraffin), Western Blot
OTI5D11
Unconjugated
EIF4E
Liquid
EIF4E
Full length human recombit protein of human EIF4E produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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