EIF4E Mouse anti-Human, Clone: OTI6C3, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA502896

Catalog No. 50-167-3896

Description

All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.

Specifications

• Antigen: EIF4E
• Classification: Monoclonal
• Concentration: 0.52 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P06730
• Gene Alias: AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 1977

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6C3
• Conjugate: Unconjugated
• Gene: EIF4E
• Format: Liquid
• Gene Symbols: EIF4E
• Immunogen: Full length human recombit protein of human EIF4E produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human