ELF1 Mouse anti-Human, Clone: OTI3D3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527425
DescriptionEts-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA-binding activity of all members of the Ets gene family. Elf-1 is a lymphoid-specific member of the Ets family that has been shown to regulate inducible gene expression during T cell activation. Elf-1 contains a sequence motif that is highly related to the Rb-binding sites common to several viral oncoproteins and binds to the pocket region of Rb both in vivo and in vitro.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|E74 like factor 1; E74-like factor 1; ELF 1; ELF1; ELF1; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; ets-related transcription factor; ETS-related transcription factor Elf-1; mElf 1;|
|-20° C, Avoid Freeze/Thaw Cycles|
|Full length human recombit protein of ELF1 produced in E.coli|
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