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ELOA Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550839

Catalog No. PA550839


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Description

Description

The antibody detects endogenous levels of total Elongin A protein.

This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.
Specifications

Specifications

ELOA
Polyclonal
Unconjugated
ELOA
Liquid
ELOA
Synthetic peptide corresponding to a region derived from internal residues of human transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.9 mg/mL
PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Q14241
EloA, SIII, TCEB3A, SIII p110
Rabbit
IgG
100 μL
-20°C
Primary
6924
Documents
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