ELOVL6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 211601AP
DescriptionLipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q920L5, Q920L6, Q9H5J4|
|ELOVL6, FACE, FAE, Fatty acid elongase 2, Fatty acyl CoA elongase, hELO2, LCE, Long chain fatty acyl elongase|
|170439, 171402, 79071|
|Immunohistochemistry (Paraffin), Western Blot|
|ELOVL6 Fusion Protein Ag14163|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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