EMD Millipore™ Cathepsin D, Human Liver, Protein

Manufacturer: EMD Millipore 21940130U

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Catalog No. 21-940-130U

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    Format Lyophilized
    Formulation Lyophilized from 2mM sodium phosphate buffer, pH 6.5.
    Preparation Method Sterile H2O or aqueous buffers. Please see vial label for lot-specific reconstitution volume.
    Purification Method SDS-PAGE
    Purity ≥90%
    Quantity 30U
    Recombinant No
    Immunogen Cathepsin D
    Storage Requirements Following reconstitution, aliquot and freeze (−20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C. Keep on ice when working with material. When product is brought to its active pH (3.3), autolysis occurs.
    Regulatory Status RUO

    Native cathepsin D from human liver. A major lysosomal aspartyl protease produced as a 52kDa proenzyme. Overexpression of cathepsin D in human breast cancers is associated with higher risk of relapse and metastasis. Cathepsin D degrades extracellular matrix and releases growth factors bound to the matrix.

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