MilliporeSigma™ Cobra Venom Factor, Naja naja kaouthia, Protein

Supplier:  MilliporeSigma™ 2335521MG

Catalog No. 23-355-21MG

Description

Native cobra venom factor from Naja naja kaouthia. Glycoprotein composed of three non-identical disulfide-bonded subunits with M.W. of 68kDa (α), 48kDa (β), and 30kDa (γ). Cobra venom factor (CVF) is a structural and functional analog of cobra, as well as mammalian C3. Thus, in the presence of Factor B, Factor D, and Mg²⁺, CVF can form a stable CVF,Bb complex that is a C3/C5 convertase enzyme; however, the CVF,Bb complex is not susceptible to regulation by Factors H and I. Four to six μg of purified CVF are equal to 1.0 unit of functional activity as measured by the method of Cochrane, et al.

Specifications

• Concentration: Concentration on Label
• Purification Method: SDS-PAGE
• Immunogen: Cobra Venom Factor
• Regulatory Status: RUO
• Recombinant: Native
• Purity or Quality Grade: ≥95%

• Formulation: In PBS, pH 7.2.
• Quantity: 1mg
• Storage Requirements: Following initial thaw, aliquot and freeze (−70°C).
• Species: N. kaouthia
• Form: Liquid