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MilliporeSigma™ PTEN, HisTag™ and Stag™ Human Recombinant Protein, S. frugiperda

Manufacturer:  MilliporeSigma™ 48140910UG

Catalog No. 48-140-910UG


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Description

Description

Full-length, recombinant, human PTEN (GenBank target symbol = PTEN, ACC No. BC_005821) fused at N-terminus to a His·Tag™ and S·Tag™ sequences and expressed in S. frugiperda insect cells. PTEN is a tumor suppressor that is frequently found mutated in human cancers. It serves as a lipid phosphatase and negative regulator of the PI-3K/Akt pathway. Absence of functional PTEN results in constitutive activation of Akt and mTOR kinases.
Specifications

Specifications

Concentration on Label
In 150mM NaCl, 50mM Tris-HCl, 5mM DTT, 1mM EDTA, 50% glycerol, pH 7.5.
≥80%
S. frugiperda
Following initial thaw, aliquot and freeze (−70°C).
His·Tag™ and S·Tag™
Yes
Liquid
SDS-PAGE
10μg
PTEN
RUO
Human
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