MilliporeSigma PTEN, HisTag and Stag Human Recombinant Protein, S. frugiperda
Manufacturer: MilliporeSigma 48140910UG
DescriptionFull-length, recombinant, human PTEN (GenBank target symbol = PTEN, ACC No. BC_005821) fused at N-terminus to a His·Tag and S·Tag sequences and expressed in S. frugiperda insect cells. PTEN is a tumor suppressor that is frequently found mutated in human cancers. It serves as a lipid phosphatase and negative regulator of the PI-3K/Akt pathway. Absence of functional PTEN results in constitutive activation of Akt and mTOR kinases.
|Concentration on Label|
|In 150mM NaCl, 50mM Tris-HCl, 5mM DTT, 1mM EDTA, 50% glycerol, pH 7.5.|
|Following initial thaw, aliquot and freeze (−70°C).|
|His·Tag™ and S·Tag™|
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