Mouse anti-EMMPRIN/CD147, Clone: CB43, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2445360.02MG
Ensure accurate, reproducible results in Flow Cytometry, ImmunofluorescenceEMMPRIN/CD147 Monoclonal antibody specifically detects EMMPRIN/CD147 in Human samples. It is validated for Flow Cytometry, Immunofluorescence.
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|5F7, basigin, basigin (Ok blood group), CD147, CD147 antigen, Collagenase stimulatory factor, EMMPRINTCSF, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, M6, OK, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor|
|Cancer, Signal Transduction, Vision|
|Flow Cytometry, Immunofluorescence|
|Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml|
|Native human leucocytes|
|Protein A or G purified|
|Store at 4C.|
|CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.|
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