EMR3 Hamster anti-Human, Janelia Fluor 549, Clone: 3D7, Novus Biologicals
Hamster Monoclonal Antibody
Manufacturer: Novus Biologicals NB10065935JF549
DescriptionEMR3 Monoclonal antibody specifically detects EMR3 in Human samples. It is validated for Flow Cytometry.
|ARHO-EMR3-CD97 (EGF1) transfectants.|
|Protein G purified|
|GPCR, Immunology, Innate Immunity|
|Janelia Fluor 549|
|50mM Sodium Borate with 0.05% Sodium Azide|
|egf-like module containing, mucin-like, hormone receptor-like 3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3, egf-like module-containing mucin-like receptor 3|
|Store at 4°C in the dark.|
|NB100-65935 recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.|
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