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Endoglin/CD105, Rabbit anti-Mouse, Clone: MJ7/18, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP2810850.2MG

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Catalog No. NB015692


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Description

Description

Endoglin/CD105 Monoclonal antibody specifically detects Endoglin/CD105 in Mouse Samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation.
Specifications

Specifications

Endoglin/CD105
MJ7/18
Unconjugated
PBS
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
Rabbit
IgG Kappa
0.2 mg
Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Primary
2022
Mouse
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
1 mg/mL
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Purified
ENG
MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Protein A purified
RUO
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal
MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
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