Enolase 2/Neuron-specific Enolase Mouse anti-Human, Mouse, Rat, PE-Cyanine7, Clone: ENO2/1375, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP254452PECY7
DescriptionEnolase 2/Neuron-specific Enolase Monoclonal antibody specifically detects Enolase 2/Neuron-specific Enolase in Human, Mouse, Rat samples. It is validated for Flow Cytometry.
|Enolase 2/Neuron-specific Enolase|
|A synthetic peptide corresponding to aa416-433 of human NSE gamma.|
|Protein A or G purified|
|Cancer, Cellular Markers, Neuronal Cell Markers, Neuroscience|
|Human, Mouse, Rat|
|PBS with 0.05% Sodium Azide|
|2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, EC 184.108.40.206, Enolase 2, enolase 2 (gamma, neuronal), gamma-enolase, Neural enolase, neuron specific gamma enolase, neurone-specific enolase, Neuron-specific enolase, NSE|
|Store at 4°C in the dark. Do not freeze.|
|Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.|
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