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Enolase 2/Neuron-specific Enolase Mouse anti-Human, PE-Cyanine7, Clone: ENO2/1462, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP259603PECY7

Catalog No. N259603PEC7


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Description

Description

Enolase 2/Neuron-specific Enolase Monoclonal antibody specifically detects Enolase 2/Neuron-specific Enolase in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

Enolase 2/Neuron-specific Enolase
ENO2/1462
Flow Cytometry
Conjugated, Purified
ENO2
A synthetic peptide of human NSE gamma (around aa416-433; exact sequence is proprietary)
Protein A or G purified
Cancer, Cellular Markers, Neuronal Cell Markers, Neuroscience
Primary
2026.0
Human
Flow Cytometry
PE-Cyanine7
PBS with 0.05% Sodium Azide
2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, EC 4.2.1.11, Enolase 2, enolase 2 (gamma, neuronal), gamma-enolase, Neural enolase, neuron specific gamma enolase, neurone-specific enolase, Neuron-specific enolase, NSE
Mouse
IgG2b
0.1 mL
Store at 4°C in the dark. Do not freeze.
Monoclonal
The specificity of this monoclonal antibody to human Enolase 2/Neuron-specific Enolase was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. Recognizes a protein of about 50kDa, which is identified as gamma -enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.
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