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EO 1428, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Selective inhibitor of p38α and p38β2 that displays no activity at p38γ, p38δ, ERK1/2 and JNK1. Inhibits production of inflammatory cytokines including IL-8, TNF-α, IL-6, IL-1β and IL-10 (IC50 values are 4, 5, 17, 30 and 74 nM respectively). Displays anti-inflammatory activity in murine models of acute and chronic dermatitis.
Specifications
Quantity | 50 mg |
Formula Weight | 415.71 |
Percent Purity | >98% |
Chemical Name or Material | EO 1428 |
Safety and Handling
Recommended Storage | Store at +4°C |
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