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EOMES Rat anti-Human, Mouse, Clone: 21Mags8, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$117.00 - $249.00

Specifications

Antigen EOMES
Clone 21Mags8
Target Species Human, Mouse
Conjugate Unconjugated
Isotype IgG2a, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-130-75 Non-distribution product as customer accommodation.
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Invitrogen
14487680
25 μg
Each for $117.00
Add to cart
 
50-130-76 Non-distribution product as customer accommodation.
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Invitrogen
14487682
100 μg
Each for $249.00
Add to cart
 
Description

Description

Description: This 21Mags8 antibody recognizes Eomesodermin (Eomes), also known as T-box brain 2 (TBR2). Eomes is a T-box transcription factor that is highly homologous to T-bet, which is essential during trophoblast development and gastrulation in most vertebrates. In the immune system, Eomes controls the differentiation of effector and memory CD8+ T cells, as well as natural killer (NK) cells. Expression of Eomes in these cells correlates with high expression of CD122, the common beta-chain of the IL-2R and IL-15R. Note: For detection of mouse Eomes, we recommend 12-4875 and 51-4875 and for detection of human Eomes, we recommend 51-4877 due to the brighter staining intensity of these products compared to clone 21Mags8. Applications Reported: This 21Mags8 antibody has been reported for use in flow cytometric analysis, and immunoblotting (WB). Applications Tested: This 21Mags8 antibody has been tested by western blot analysis of mouse splenocytes. As a starting concentration, this antibody can be used at 2 µg/mL. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

TBR2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar protein disrupted in mice is shown to be essential during trophoblast development and gastrulation. TBR2 plays a role in brain development and is required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex.
Specifications

Specifications

EOMES
Human, Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C
21Mags8
Unconjugated
Flow Cytometry, Western Blot
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.

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