EPAS1 Monoclonal Antibody (OTI6G3), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809645

Catalog No. 50-168-2929

Description

HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.

Specifications

• Antigen: EPAS1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q99814
• Gene Symbols: EPAS1
• Immunogen: Human recombit protein fragment corresponding to amino acids 584-870 of human EPAS1 produced in E.coli
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI6G3
• Conjugate: Unconjugated
• Gene: EPAS1
• Gene Alias: ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2034
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid