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EphA2, Human anti-Human, Clone: 1C1, Novus Biologicals™

Human Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP2810690.025MG

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Catalog No. NB015313


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Description

Description

EphA2 Monoclonal antibody specifically detects EphA2 in Human Samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunofluorescence, Blocking Assay.
Specifications

Specifications

EphA2
1C1
Unconjugated
PBS
ARCC2, EC 2.7.10, EC 2.7.10.1, ECKepithelial cell receptor protein tyrosine kinase, EPH receptor A2, EphA2, ephrin type-A receptor 2, Epithelial cell kinase, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK
Human
IgG1 Kappa
0.025 mg
Cancer, Protein Kinase
Primary
1969
Human
Western Blot, Flow Cytometry, ELISA, Immunofluorescence, Blocking Assay
1 mg/mL
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Block/Neutralize
Purified
EPHA2
1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1.
Protein A purified
RUO
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Monoclonal
1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ∽0.8 nM; Fab KD ∽140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.
SDS
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