EphA2, Human anti-Human, Clone: 1C1, Novus Biologicals™
Human Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2810690.2MG
DescriptionEphA2 Monoclonal specifically detects EphA2 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Block/Neutralize.
|ARCC2, EC 2.7.10, EC 188.8.131.52, ECKepithelial cell receptor protein tyrosine kinase, EPH receptor A2, EphA2, ephrin type-A receptor 2, Epithelial cell kinase, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK|
|Cancer, Protein Kinase|
|Western Blot, Flow Cytometry, ELISA, Immunofluorescence, Blocking Assay|
|Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Block/Neutralize|
|1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1.|
|Protein A purified|
|Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ∽0.8 nM; Fab KD ∽140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.|
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