EphA2 Rabbit anti-Human, Alexa Fluor 750, Clone: 1C1, Novus Biologicals
Rabbit Monoclonal Antibody
Manufacturer: Novus Biologicals NBP252677AF750
DescriptionEphA2 Monoclonal antibody specifically detects EphA2 in Human samples. It is validated for Western Blot,Flow Cytometry,ELISA,Immunofluorescence.
|Western Blot, Flow Cytometry, ELISA, Immunofluorescence|
|ARCC2, EC 2.7.10, EC 220.127.116.11, ECKepithelial cell receptor protein tyrosine kinase, EPH receptor A2, EphA2, ephrin type-A receptor 2, Epithelial cell kinase, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK|
|Store at 4°C in the dark.|
|1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ~0.8 nM; Fab KD ~140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.|
|ELISA, Flow Cytometry, Immunofluorescence, Western Blot|
|Alexa Fluor™ 750|
|50 mM sodium borate with 0.05% sodium azide|
|1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1.|
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