Invitrogen™ EphA4 Monoclonal Antibody (M280)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA547715

Catalog No. PIMA547715

Description

This antibody detects 95 and 120 kDa* bands corresponding to EphA4 in Western blots of HUVEC cells and a 120 kDa band in mouse brain tissue.

EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA4 encodes a protein that binds ephrin-A ligands.

Specifications

• Antigen: EphA4
• Classification: Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: P54764, Q03137
• Gene Symbols: EPHA4
• Immunogen: Clone M280 was generated from a recombinant protein corresponding to amino acids in the N-terminal region of human EphA4. This region has less than 50% homology to similar regions in other EphA and EphB family members.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: M280
• Conjugate: Unconjugated
• Gene: EPHA4
• Gene Alias: 2900005C20Rik; AI385584; Cek8; Cek8 protein; EK8; epa4; EPH receptor A4; Epha4; EPH-like kinase 8; Ephrin type-A receptor 4; Hek8; rb; receptor protein-tyrosine kinase HEK8; RGD1560587; Sek; Sek1; Tyro1; TYRO1 protein tyrosine kinase; tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor SEK; tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase TYRO1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 13838, 2043, 316539
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid