Invitrogen™ EphB6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534785

Catalog No. PIPA534785

Description

Recommended positive controls: HL-60. Predicted reactivity: Mouse (93%), Rat (93%), Rhesus Monkey (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

Specifications

• Antigen: EphB6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: EPHB6
• Gene Alias: Cekl; chicken eph/elk receptor-like protein; EPB6; EPH receptor B6; EPHB6; EphB6v; Epherin B6; Epherin receptor B6; ephrin type A receptor; ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MEP; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2051
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.78 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O15197
• Gene Symbols: EPHB6
• Immunogen: Recombinant fragment corresponding to a region within amino acids 541 and 879 of Eph Receptor B6 (Uniprot ID#O15197).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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