Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-1, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in affinity purification, immunoprecipitation and flow cytometry experiments.

Manufacturer:  Thermo Scientific™ MS268P1

 View more versions of this product

Catalog No. MS268P1

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Obtain accurate, reproducible results in affinity purification, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-1, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 528

Isotype: IgG2a

Species Reactivity: Human and Dog. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Purified EGFR from A431 cells

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not suitable)
  • Affinity Purification
  • Blocks EGF/TGFα-induced Activation of EGFR
  • Inhibits Binding of EGFR Ab-2 (clone 225) to EGFR
  • Inhibits Proliferation of A431 Cells
  • Arrests Tumor Growth in vivo
  • Immunoprecipitation (Native only)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Epidermal Growth Factor Receptor /EGFR Ab-1
Monoclonal
200μg/mL
Concentrated
Purified EGFR from A431 cells
500μL
EGFR Family
Primary
Canine, Human
Flow Cytometry, Immunoprecipitation
528
Unconjugated
Murine
IgG2a
RUO
Primary
Monoclonal
SDS
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit