Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Epidermal Growth Factor Receptor/EGFR Ab-10 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation experiments.

Supplier:  Epredia MS378PABX

 View more versions of this product

Catalog No. MS378PABX

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 111.6

Isotype: IgG1

Species Reactivity: Human. Not mouse and rat.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells; Skin, Placenta or Squamous cell CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Native only)
  • Effect on EGF Binding (Inhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Epidermal Growth Factor Receptor/EGFR Ab-10
Monoclonal
1mg/mL
Mouse
200 μL
EGFR Family
Human
IgG1
Immunohistochemistry (Paraffin), Immunoprecipitation
111.6
Unconjugated
Extracellular domain of human recombinant EGFR protein
RUO
Primary
Concentrated
Product Suggestions

Product Suggestions

SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit