Epidermal Growth Factor Receptor/EGFR Ab-11 Mouse Monoclonal Antibody, Epredia™

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments.

Supplier:  Epredia MS396P1ABX

Catalog No. MS396P1ABX

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 199.12

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Extracellular domain

Immunogen: Extracellular domain of human recombinant EGFR protein

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

• Western Blotting
• Immunoprecipitation (Native only)
• Effect on EGF Binding (Noninhibitory)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Epidermal Growth Factor Receptor/EGFR Ab-11
• Clone: 199.12
• Conjugate: Unconjugated
• Immunogen: Extracellular domain of human recombinant EGFR protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated

• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: EGFR Family
• Target Species: Human
• Isotype: IgG2a