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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-3, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence, immunoprecipitation and flow cytometry experiments.

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-3
Clone EGFR.1
Applications Flow Cytometry
Classification Monoclonal
Format Concentrated
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Products 5
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS311B0
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Thermo Scientific™
MS311B0
200μg/mL Biotin 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS311P0
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Thermo Scientific™
MS311P0
200μg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS311P1
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Thermo Scientific™
MS311P1
200μg/mL Unconjugated 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS311P1ABX
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Thermo Scientific™
MS311P1ABX
1mg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
MS311B1
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Thermo Scientific™
MS311B1
200μg/mL Biotin 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-3, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: EGFR.1

Isotype: IgG2b/κ

Species Reactivity: Human and Horse. Does not react with mouse. Others not known.

Epitope: aa 6-273

Immunogen: A431 human epidermoid cells

Molecular Weight: 170 kDa (wild type)

Positive Control: A431 cells express only the intact and not the vIII variant of EGFR. HC2 20 d2 cells express the vIII variant. In normal breast, ducts and lobules show diffuse cytoplasmic staining.

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Frozen only)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Immunoprecipitation (Native only)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Epidermal Growth Factor Receptor/EGFR Ab-3
Flow Cytometry
Concentrated
RUO
Primary
IgG2b kappa
EGFR.1
Monoclonal
Murine
EGFR Family
A431 human epidermoid cells
SDS
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