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Epidermal Growth Factor Receptor (EGFR) Rabbit Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ EGFR, Rabbit Monoclonal Antibody.

Supplier:  Epredia RM2111RQ

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Catalog No. RM2111RQ

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.


Description

Description

EGFR is a type I receptor tyrosine kinase with sequence homology to c-erbB1, B2, B3, B4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-alpha (TGF-alpha), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, colon, lung, stomach, head and neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Rabbit

Clone: EP38Y

Species Reactivity: Human. Others not tested.

Ig Isotype: Rabbit IgG

Epitope: Not determined

Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR

Molecular Weight: 175 kDa

Positive Control: Squamous carcinoma

Cellular Localization: Cell membrane and occasional cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
Specifications

Specifications

EGFR
Monoclonal
Unconjugated
A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR
Primary
Immunohistochemistry
EP38Y
Rabbit
12 mL
Ready-to-Use
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